Putting aging on ICE.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 36889279.
- Also identified by DOI 10.1016/j.cmet.2023.02.012 and PMC identifier 10592682.
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Abstract
A recent report by Yang et al. in Cell demonstrates that faithful DNA double-strand breaks and repair cycles phenocopy many aspects of aging in mice. Whether this progeroid phenotype is caused by a loss of epigenetic information remains to be conclusively determined.
Medical subject headings
- DNA Repair
- DNA Breaks, Double-Stranded