Translating from mouse to man to better understand immune-mediated inflammatory diseases.

Aschenbrenner, Dominik; Siegel, Richard M · Cell Rep Med · 2023

basic_science · Level V

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Abstract

Lilja et al.<sup>1</sup> explore single-cell transcriptomes across multiple organs of mice with collagen-induced arthritis. They apply network analysis to prioritize functional pathways that support or suppress inflammation and integrate findings with tissue transcriptomics in human immune-mediated inflammatory diseases.

Medical subject headings