Increased gestational palmitic acid predisposes offspring to congenital heart disease.

Lv, Yang; Gao, Ri-Feng; Yang, Chen-Xi; Xu, Ying-Jia; Yang, Yi-Qing · Cell Rep Med · 2023

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Abstract

Identification of the causes for congenital heart disease (CHD) is a prerequisite for precise prevention and personalized treatment of CHD. Zhao et al.<sup>1</sup> show increased that gestational serum palmitic acid (PA) predisposes offspring to CHD by perturbating the MARS/K-Hcy/GATA4 signaling pathway.

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