Terminally Exhausted CD8+ T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 36971604.
- Also identified by DOI 10.1158/0008-5472.CAN-22-3864.
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Abstract
Cross-talk with TTEX CD8+ T cells mediated by the VEGFR2 axis induces aggressive properties in cancer stem cells to promote tumor progression.
Medical subject headings
- Programmed Cell Death 1 Receptor
- Neoplasms