Breaking Up Isn't Hard to Do: Isolating Cell-free DNA Fragments in Osteosarcoma.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 36976253.
- Also identified by DOI 10.1158/1078-0432.CCR-23-0390.
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Abstract
The novel use of blood-based biospecimens from a retrospective cohort of 50 patients with osteosarcoma was recently studied. The potential clinical utility of sorting cell-free DNA by fragment size was defined, with shorter tumor-specific DNA enrichment providing prognostic value and allowing for streamlined molecular profiling of circulating tumor material. See related article by Udomruk et al., p. 2085.
Medical subject headings
- Cell-Free Nucleic Acids
- Osteosarcoma
- Bone Neoplasms