A Self-Propagating c-Met-SOX2 Axis Drives Cancer-Derived IgG Signaling That Promotes Lung Cancer Cell Stemness.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 36989345.
- Also identified by DOI 10.1158/0008-5472.CAN-22-2733.
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Abstract
Sialylated cancer IgG activates c-Met-SOX2 signaling to promote stemness properties in cancer cells and can be targeted to suppress tumor growth.
Medical subject headings
- Lung Neoplasms