T cell biomarkers come to the fore in cancer immunotherapy.

Sheriff, Lozan; Copland, Alastair; Bending, David · Cell Rep Med · 2023

review · Level V

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Abstract

A comprehensive study by van der Sluis et al.<sup>1</sup> demonstrates immunotherapeutic targeting of OX40 and PD-L1 results in enhanced tumor clearance, which is linked to the dynamic emergence of distinct subsets of CD8<sup>+</sup> T cells.

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