Early swallowing intervention after free flap reconstruction for oral cancer: A systematic review and meta-analysis.

Abstract

This study aimed to summarize the state of current literature and evaluate evidence for timing, methods, and effects of early intervention in patients after free flap reconstruction. A comprehensive search was conducted in nine databases. The methodological quality of literature was assessed according to the JBI Critical Appraisal Tools. Eight studies were finally included. Most studies started the intervention within 1 to 2 weeks after surgery with multiple swallowing training measures. The results of meta-analysis showed that swallowing intervention could improve swallowing function (SMD = -1.03, 95%CI [-1.37, -0.69], Z = 5.95, p < 0.01) and the quality of life (SMD = 1.52, 95%CI [0.97, 2.07], Z = 5.43, p < 0.01). Early swallowing intervention can improve patients' swallowing function and short-term quality of life. We can only summarize the basic consensus of the studies on early swallowing intervention, and rigorous trials are needed in the future.