PSMA PET/CT Detection of Chondromyxoid Fibroma.

Jang, Albert; Caputo, Sydney A; Hawkins, Madeline E; Talbert, Joshua E; Sartor, Oliver · Clin Nucl Med · 2023

case_report · Level V

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Abstract

A 61-year-old man underwent a piflufolastat 18 F prostate-specific membrane antigen (PSMA) PET/CT scan due to a rising prostate-specific antigen level. The scan noted a focal cortical erosion on the CT scan in the right anterolateral tibia, and the PET showed an SUV max of 4.08. A biopsy of this lesion revealed a chondromyxoid fibroma. This rare case of a PSMA PET-positive chondromyxoid fibroma illustrates the importance of radiologists and oncologists not to assume an isolated bone lesion on a PSMA PET/CT scan as a bone metastasis from prostate cancer.

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