Chemical reprogramming takes the fast lane.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 37028396.
- Also identified by DOI 10.1016/j.stem.2023.03.001.
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Abstract
Small molecule-induced cell fate transitions are characterized by low efficiency and slow kinetics. An optimized chemical reprogramming approach now facilitates the robust and rapid conversion of somatic cells to pluripotent stem cells, unlocking exciting avenues to study and manipulate human cell identity.
Medical subject headings
- Pluripotent Stem Cells
- Induced Pluripotent Stem Cells