Human hematopoietic stem cells expand beyond cytokines.

Van Huizen, Alanna; McKinney-Freeman, Shannon · Cell Stem Cell · 2023

editorial · Level V

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Abstract

The paucity of hematopoietic stem cells (HSCs) presents a challenge for both transplantation and the study of HSCs.<sup>1</sup> Sakurai et al.<sup>2</sup> now present a cytokine-free culture system for robust ex vivo expansion of functional human HSCs that may lead to exciting clinical outcomes.

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