The problem of selection bias in studies of pre-mRNA splicing.
Where this comes from
- Record sourced from PubMed, PMID 37031238.
- Also identified by DOI 10.1038/s41467-023-37650-2 and PMC identifier 10082818.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Here we demonstrate how selection bias in studies of pre-mRNA splicing can inadvertently lead to inaccurate biological conclusions which nevertheless appear statistically robust. We argue that this may be a pervasive problem with potentially significant consequences for the field.
Medical subject headings
- RNA Precursors
- RNA Splicing