CRISPR-based assays for low-resource settings.

Huang, Zhen; Lyon, Christopher J; Hu, Tony Y · Nat Rev Bioeng · 2023

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Abstract

CRISPR-based assays can be adopted as ultrasensitive molecular diagnostics in resource-limited settings, but point-of-care applications must address additional requirements. Here, we discuss the major obstacles for developing these assays and offer insights into how to surmount them.