Influence of Timing of Maternal Pertussis Immunization on the Avidity of Transferred Antibodies in Term and Preterm Neonates.

Sartoretti, Julie; Fontannaz, Paola; Martinez de Tejada, Begoña; Othenin-Girard, Véronique; Chilin, Antonina; Lemaître, Barbara; Blanchard-Rohner, Géraldine; Siegrist, Claire-Anne et al. · Clin Infect Dis · 2023

prospective_cohort · Level II

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Abstract

The timing of maternal pertussis vaccination influences the titers of cord-blood anti-pertussis antibodies. Whether it affects their avidity is unknown. We demonstrate in 298 term and 72 preterm neonates that antibody avidity is independent of the timing of maternal vaccination, whether comparing second with third trimester or intervals before birth.

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