ctDNA Monitoring for Small Cell Lung Cancer: Ready for Prime Time?

Pellini, Bruna; Chaudhuri, Aadel A · Clin Cancer Res · 2023

editorial · Level V

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Abstract

Small cell lung cancer (SCLC) is the deadliest form of lung cancer and has few precision medicine approaches available. A recent study analyzed circulating tumor DNA (ctDNA) in 33 patients with extensive-stage SCLC and showed that ctDNA levels and response patterns correlate strongly with clinical response and survival outcomes. See related article by Sivapalan et al., p. 2310.

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