CAND1 orchestrates CRLs through rock and roll.

Xie, Yuan; Zhao, Minglei · Cell · 2023

editorial · Level V

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Abstract

Proper regulation of protein degradation is essential for cell physiology. In the current issue of Cell, Baek et al. elucidated how a large class of ubiquitin ligase, known as CRL, is assembled and disassembled through a key regulator, CAND1.

Medical subject headings