A precision environmental health approach to prevention of human disease.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 37117186.
- Also identified by DOI 10.1038/s41467-023-37626-2 and PMC identifier 10147599.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Human health is determined by the interaction of our environment with the genome, epigenome, and microbiome, which shape the transcriptomic, proteomic, and metabolomic landscape of cells and tissues. Precision environmental health is an emerging field leveraging environmental and system-level ('omic) data to understand underlying environmental causes of disease, identify biomarkers of exposure and response, and develop new prevention and intervention strategies. In this article we provide real-life illustrations of the utility of precision environmental health approaches, identify current challenges in the field, and outline new opportunities to promote health through a precision environmental health framework.
Medical subject headings
- Humans
- Proteomics
- Health Promotion
- Environmental Health
- Microbiota
- Biomarkers