Remaining true to one's identity.
Where this comes from
- Record sourced from PubMed, PMID 37117630.
- Also identified by DOI 10.1038/s43587-021-00113-8 and PMC identifier 10835580.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The ability to remain true to cellular identity and function is lost during aging and carcinogenesis when DNA damage triggers inflammation that progressively erodes homeostatic cues. Shalabi et al. show that these losses are accelerated in patients with germline cancer mutations in DNA repair genes and are independent of chronological age.
Medical subject headings
- Self Concept
- Aging