GDF11 reverses mood and memory declines in aging.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 37118123.
- Also identified by DOI 10.1038/s43587-023-00362-9 and PMC identifier 10372845.
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Abstract
Aging is known to be associated with a decline in memory and mood, but the molecular mechanisms that underlie these changes remain unclear. Moigneu, Abdellaoui and colleagues show that growth differentiation factor 11 reverses deficits in these functions in aged mice, pointing the way towards a novel pro-mnemonic and antidepressant therapeutic target.
Medical subject headings
- Aging
- Growth Differentiation Factors