VirPipe: an easy-to-use and customizable pipeline for detecting viral genomes from Nanopore sequencing.

Kim, Kijin; Park, Kyungmin; Lee, Seonghyeon; Baek, Seung-Hwan; Lim, Tae-Hun; Kim, Jongwoo; Manavalan, Balachandran; Song, Jin-Won et al. · Bioinformatics · 2023

basic_science · Level V

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Abstract

Detection and analysis of viral genomes with Nanopore sequencing has shown great promise in the surveillance of pathogen outbreaks. However, the number of virus detection pipelines supporting Nanopore sequencing is very limited. Here, we present VirPipe, a new pipeline for the detection of viral genomes from Nanopore or Illumina sequencing input featuring streamlined installation and customization. VirPipe source code and documentation are freely available for download at https://github.com/KijinKims/VirPipe, implemented in Python and Nextflow.

Medical subject headings