Remote control of autophagy and metabolism in the liver.
Where this comes from
- Record sourced from PubMed, PMID 37137284.
- Also identified by DOI 10.1016/j.cmet.2023.04.009.
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Abstract
Systemic control of homeostatic processes is of fundamental importance for survival and adaptation in metazoans. In this issue of Cell Metabolism, Chen and colleagues identify and methodically dissect a signaling cascade that is mobilized by the agouti-related peptide (AgRP)-expressing neurons in the hypothalamus, to ultimately modulate autophagy and metabolism in the liver upon starvation.
Medical subject headings
- Autophagy
- Liver
- Hypothalamus