Neurotransmitters arrive to control systemic autoimmunity.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 37137285.
- Also identified by DOI 10.1016/j.cmet.2023.04.004.
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Abstract
Immune cell microenvironment plays a major role in the aberrant function of immune cells in systemic lupus erythematosus. Zeng and co-authors show that in human and murine lupus, splenic stromal cell-derived acetylcholine switches B cell metabolism to fatty acid oxidation and promotes B cell autoreactivity and disease development.
Medical subject headings
- Autoimmunity
- Lupus Erythematosus, Systemic