Do flies dream of protein? How the gut regulates sleep depth.
Level V
Where this comes from
- Record sourced from PubMed, PMID 37137287.
- Also identified by DOI 10.1016/j.cmet.2023.04.001.
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Abstract
A recent study by Titos et al. in Cell shows that protein-rich diets are strong modulators of sleep depth in Drosophila and identifies the gut-secreted neuropeptide CCHa1 as the mediator of this effect. In the brain, CCHa1 controls dopamine release from a small set of neurons, thereby modulating arousability by integrating internal state with sensory information.
Medical subject headings
- Drosophila Proteins
- Neuropeptides