Energy saver: Monocytes hibernate in bone marrow upon fasting.
Where this comes from
- Record sourced from PubMed, PMID 37137288.
- Also identified by DOI 10.1016/j.cmet.2023.04.008.
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Abstract
Immune functions are influenced by the nutritional state. In a recent publication in Immunity, Janssen et al. unveil that a fasting-induced glucocorticoid release makes monocytes move from blood into the bone marrow. Upon refeeding, these chronologically older monocytes are again released and exert detrimental effects during bacterial infection.
Medical subject headings
- Monocytes
- Bone Marrow