A Genomic Perspective on the Near-term Impact of Doxycycline Post-exposure Prophylaxis on Neisseria gonorrhoeae Antimicrobial Resistance.
basic_science · Level V
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- Record sourced from PubMed, PMID 37138444.
- Also identified by DOI 10.1093/cid/ciad279 and PMC identifier 10495131.
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Abstract
Pre-existing tetracycline resistance in Neisseria gonorrhoeae limits the effectiveness of post-exposure prophylaxis (PEP) with doxycycline against gonorrhea, and selection for tetracycline resistance may influence prevalence of multi-drug resistant strains. Using genomic and antimicrobial susceptibility data from N. gonorrhoeae, we assessed the near-term impact of doxycycline PEP on N. gonorrhoeae resistance.
Medical subject headings
- Neisseria gonorrhoeae
- Gonorrhea