An instrument-free, programmable approach for nucleic acid detection.

Nat Biomed Eng · 2023

basic_science · Level V

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Abstract

INSPECTR is a technique for detecting nucleic acids that couples the sensitivity and specificity of nucleic acid splinted ligation with the versatile readouts of cell-free gene expression. The result is an ambient-temperature workflow that enables the detection of pathogenic viruses at low copy numbers.

Medical subject headings