hPSCs-derived Schwann cells serve for disease modeling and drug discovery.
basic_science · Level V
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- Record sourced from PubMed, PMID 37146574.
- Also identified by DOI 10.1016/j.stem.2023.04.013.
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Abstract
In this issue, Majd et al.<sup>1</sup> derive Schwann cells from human pluripotent stem cells (hPSCs), which can be used to study Schwann cell development and physiology and model diabetic neuropathy. hPSC-derived Schwann cells possess the molecular features of primary Schwann cells and are capable of myelination in vitro and in vivo.
Medical subject headings
- Schwann Cells
- Pluripotent Stem Cells