Perspectives on validation of clinical predictive algorithms.

de Hond, Anne A H; Shah, Vaibhavi B; Kant, Ilse M J; Van Calster, Ben; Steyerberg, Ewout W; Hernandez-Boussard, Tina · NPJ Digit Med · 2023

review · Level V

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Abstract

The generalizability of predictive algorithms is of key relevance to application in clinical practice. We provide an overview of three types of generalizability, based on existing literature: temporal, geographical, and domain generalizability. These generalizability types are linked to their associated goals, methodology, and stakeholders.