Time-dependent vaccine efficacy estimation quantified by a mathematical model.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 37167285.
- Also identified by DOI 10.1371/journal.pone.0285466 and PMC identifier 10174497.
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Abstract
In this paper we calculate the variation of the estimated vaccine efficacy (VE) due to the time-dependent force of infection resulting from the difference between the moment the Clinical Trial (CT) begins and the peak in the outbreak intensity. Using a simple mathematical model we tested the hypothesis that the time difference between the moment the CT begins and the peak in the outbreak intensity determines substantially different values for VE. We exemplify the method with the case of the VE efficacy estimation for one of the vaccines against the new coronavirus SARS-CoV-2.
Medical subject headings
- COVID-19