Mapping the motion and structure of flexible proteins from cryo-EM data.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 37169930.
- Also identified by DOI 10.1038/s41592-023-01883-2 and PMC identifier 10174731.
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Abstract
A deep learning algorithm maps out the continuous conformational changes of flexible protein molecules from single-particle cryo-electron microscopy images, allowing the visualization of the conformational landscape of a protein with improved resolution of its moving parts.
Medical subject headings
- Proteins