SnapShot: Eukaryotic ribosome biogenesis I.

Hurt, Ed; Cheng, Jingdong; Baβler, Jochen; Iwasa, Janet; Beckmann, Roland · Cell · 2023

basic_science · Level V

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Abstract

Ribosome production is vital for every cell, and failure causes human diseases. It is driven by ∼200 assembly factors functioning along an ordered pathway from the nucleolus to the cytoplasm. Structural snapshots of biogenesis intermediates from the earliest 90S pre-ribosomes to mature 40S subunits unravel the mechanisms of small ribosome synthesis. To view this SnapShot, open or download the PDF.

Medical subject headings