Comment on "Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice".

Wang, Yuanyuan; Weber, Martin; Foreman, Oded; Remy, Helga; Mracsko, Eva Zsuzsanna; Hanson, Jesse E · Sci Transl Med · 2023

editorial · Level V

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Abstract

We highlight potential issues with a Western blot assay using mouse anti-caspase-1 antibody to detect cleaved caspase-1 p20 subunit in mouse brain tissue lysates.

Medical subject headings