Hebbian and homeostatic synaptic plasticity of AMPA receptors in epileptogenesis.

Curia, Giulia · Cell Rep Med · 2023

editorial · Level V

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Abstract

AMPA receptors' synaptic plasticity is involved in epileptogenesis. In this issue, Eiro et al.<sup>1</sup> demonstrate that Hebbian plasticity is responsible for increased AMPAR in focal seizures, while homeostatic plasticity induces the reduction of AMPAR in generalized onset seizures.

Medical subject headings