Learning while treating: Gain-of-function STAT6 variants in severe allergic disease.

Smith, Tukisa D; Doherty, Taylor A · Cell Rep Med · 2023

editorial · Level V

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Abstract

In an era of rapid identification of inborn errors of immunity, Sharma et al.<sup>1</sup> report novel heterozygous gain-of-function variants in the signal transducer and activator of transcription 6 (STAT6) gene in individuals with severe and early onset multi-systemic allergic disease.

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