Challenging the Prevailing Therapeutic Dogma for Prostate Cancer: The Case for an Overlap Syndrome.

Logothetis, Christopher J; Hahn, Andrew W · Eur Urol · 2024

expert_opinion · Level V

Where this comes from

Abstract

There is a need to understand what accounts for the modest impact of therapy on overall survival among men with potentially lethal prostate cancer. Given converging lines of evidence, we hypothesize that in a subset of men, prostate cancer is part of an "overlap syndrome" of age-related illnesses with shared biologic vulnerability.

Medical subject headings