Necrotizing Enterocolitis following Onasemnogene Abeparvovec for Spinal Muscular Atrophy: A Case Series.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 37211209.
- Also identified by DOI 10.1016/j.jpeds.2023.113493.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Onasemnogene abeparvovec treats spinal muscular atrophy by delivering a functional SMN1 gene. Necrotizing enterocolitis typically occurs in preterm infants. We report 2 term infants diagnosed with spinal muscular atrophy who presented with necrotizing enterocolitis after onasemnogene abeparvovec infusion. We discuss potential etiologies and propose monitoring for necrotizing enterocolitis after onasemnogene abeparvovec therapy.
Medical subject headings
- Enterocolitis, Necrotizing
- Muscular Atrophy, Spinal
- Infant, Newborn, Diseases
- Fetal Diseases
- Spinal Muscular Atrophies of Childhood