Fosmanogepix Therapy of Disseminated Fusarium Infection.

Winston, Drew J; Young, Patricia A; Schlamm, Haran T; Schiller, Gary J · Clin Infect Dis · 2023

case_report · Level V

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Abstract

Invasive Fusarium infections cause high mortality. Fosmanogepix, a first-in-class antifungal agent, has potent activity against Fusarium. A patient with acute leukemia with invasive fusariosis, probably involving the central nervous system and caused by Fusarium lactis resistant to currently available antifungal agents, was cured of her infection with fosmanogepix. Fosmanogepix was well tolerated.

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