IgA nephropathy.
Where this comes from
- Record sourced from PubMed, PMID 37225260.
- Also identified by DOI 10.3949/ccjm.90.e-s1.02.
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Abstract
Immunoglobulin A nephropathy (IgAN) is the most common glomerulonephritis in the world. The etiology is unknown but a dysregulated T-cell immune response to viral, bacterial, and food antigens activating mucosal plasma cells to produce polymeric IgA has been proposed. No serological test exists to diagnosis IgAN. A definitive diagnosis requires kidney biopsy which is not always necessary. Kidney failure occurs in 20% to 40% of patients within 10 to 20 years.
Medical subject headings
- Glomerulonephritis, IGA
- Renal Insufficiency