Acute respiratory failure-related excess mortality in pediatric sepsis.
Where this comes from
- Record sourced from PubMed, PMID 37225415.
- Also identified by DOI 10.1136/thorax-2022-219961 and PMC identifier 10953703.
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Abstract
Excess mortality risk imparted by acute respiratory failure in children is unknown. We determined excess mortality risk associated with mechanically ventilated acute respiratory failure in pediatric sepsis. Novel ICD10-based algorithms were derived and validated to identify a surrogate for acute respiratory distress syndrome to calculate excess mortality risk. Algorithm-identified ARDS was identified with specificity of 96.7% (CI 93.0 - 98.9) and sensitivity of 70.5% (CI 44.0 - 89.7). Excess risk of mortality for ARDS was 24.4% (CI 22.9 - 26.2). Development of ARDS requiring mechanical ventilation imparts modest excess risk of mortality in septic children.
Medical subject headings
- Sepsis
- Respiratory Distress Syndrome
- Respiratory Insufficiency