Significant Association of Cutavirus With Parapsoriasis en Plaques: High Prevalence Both in Skin Swab and Biopsy Samples.

Mohanraj, Ushanandini; Konttinen, Tuomas; Salava, Alexander; Väkevä, Liisa; Ranki, Annamari; Söderlund-Venermo, Maria · Clin Infect Dis · 2023

cross_sectional · Level IV

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Abstract

Cutavirus (CuV) is associated with cutaneous T-cell lymphoma (CTCL), of which parapsoriasis is a precursor. Our study reveals a significantly higher CuV-DNA prevalence in skin swabs of parapsoriasis patients (6/13; 46.2%) versus those of healthy adults (1/51; 1.96%). Eight patients (8/12; 66.7%) had CuV DNA in biopsied skin, and 4 developed CTCL.

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