Contemporary Evaluation of Salvage Radiotherapy for Prostate Cancer: Radiotherapy Dose, Field Size, and Use of Hormone Therapy.

Jiang, Tommy; Valle, Luca F; Kishan, Amar U · Eur Urol · 2023

review · Level V

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Abstract

Studies have provided high-level evidence on various aspects of salvage radiation therapy (SRT) for recurrence of prostate cancer after radical prostatectomy, including field design, dose and fractionation, and additional hormonal therapy regimens. For patients with higher prostate-specific antigen (PSA) at SRT, addition of hormonal therapy and pelvic nodal radiation will improve PSA-based endpoints. By contrast, dose escalation is not supported by level 1 evidence in this setting.

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