Circulating Tumor DNA Biomarkers for Response Assessment in Prostate Cancer.

Sartor, Oliver · Clin Cancer Res · 2023

review · Level V

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Abstract

Circulating tumor DNA (ctDNA) is measurable in the majority of metastatic castration-resistant prostate cancer patients. Data indicate that ctDNA present at baseline can serve as a prognostic biomarker and changes in the ctDNA posttreatment can rapidly predict both time to progression and survival. See related article by Tolmeijer et al., p. 2835.

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