The cellular supply-side economics for phospholipids.

Kuk, Alvin C Y; Silver, David L · Cell Metab · 2023

Level V

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Abstract

Choline is an essential nutrient, but how cells acquire it was not known. Two studies by Kenny et al. and Tsuchiya et al. identified the plasma membrane proteins FLVCR1 and FLVCR2 to be the bona fide choline transporters mediating choline uptake for de novo synthesis of phospholipids in all cells.

Medical subject headings