Prognosis to Radiation Unlocked: How Hypoxia Methylome May Hold the Key in HNSCC.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 37310809.
- Also identified by DOI 10.1158/1078-0432.CCR-23-1132 and PMC identifier 10527007.
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Abstract
Hypoxia in head and neck tumors has proven to be predictive of outcomes. Current hypoxia signatures have failed for patient treatment selection. In a recent study, the authors identified a hypoxia methylation signature as a more robust biomarker in head and neck squamous cell carcinoma and shed light into the mechanism of hypoxia-mediated treatment resistance. See related article by Tawk et al., p. 3051.
Medical subject headings
- Carcinoma, Squamous Cell
- Papillomavirus Infections
- Head and Neck Neoplasms