Unravelling the genetic architecture of human complex traits through whole genome sequencing.

Bocher, Ozvan; Willer, Cristen J; Zeggini, Eleftheria · Nat Commun · 2023

editorial · Level V

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Abstract

Whole genome sequencing has enabled new insights into the genetic architecture of complex traits, especially through access to low-frequency and rare variation. This <i>Comment</i> highlights the key contributions from this technology and discusses considerations for its use and future perspectives.

Medical subject headings