Bioengineering of bacteria for cancer immunotherapy.

Nguyen, Dinh-Huy; Chong, Ari; Hong, Yeongjin; Min, Jung-Joon · Nat Commun · 2023

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Abstract

Here, we provide a brief overview of the approaches and strategies underlying bacteria-based cancer immunotherapy (BCiT). We also describe and summarize research in the field of synthetic biology, which aims to regulate bacterial growth and gene expression for immunotherapeutic use. Finally, we discuss the current clinical status and limitations of BCiT.

Medical subject headings