FDG-Avid But Pentixafor-Negative in EBV-Associated T-Cell Lymphoproliferative Disorders.
case_report · Level V
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- Record sourced from PubMed, PMID 37335307.
- Also identified by DOI 10.1097/RLU.0000000000004747.
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Abstract
An 18-year-old woman with intermittent fever, pancytopenia, abnormal liver function, and enlarged lymph nodes and hepatosplenomegaly was clinically suspected as hemophagocytic lymphohistiocytosis. 18 F-FDG PET/CT showed increased metabolism in multiple lymph nodes, which were highly suggestive of lymphoma. No increased CXCR4 expression in lymph nodes was demonstrated on 68 Ga-pentixafor PET/CT. Subsequent right neck lymph node biopsy pathology revealed EBV-associated lymphoproliferative disorders. Our case shows that 68 Ga-pentixafor PET/CT may have potential value in differentiating EBV-associated lymphoproliferative disorders from lymphomas.
Medical subject headings
- Lymphoma
- Lymphoproliferative Disorders