Network perturbation-based biomarkers of depression and treatment response.

Müller-Dahlhaus, Florian; Bergmann, Til Ole · Cell Rep Med · 2023

basic_science · Level V

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Abstract

Using concurrent TMS-EEG, Han et al.<sup>1</sup> identified temporal and spectral signatures of depression in a prefrontal-orbitofrontal-hippocampal network, which renormalized after rTMS. This highlights the relevance of causal network perturbation for the assessment of disease-related network states and their therapeutic modulation.

Medical subject headings