Organoids as a tool in drug discovery and patient-specific therapy for head and neck cancer.

Done, Aaron J; Birkeland, Andrew C · Cell Rep Med · 2023

basic_science · Level V

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Abstract

Organoids more accurately reflect tumor microenvironment than traditional models. Millen et al. demonstrated organoids replicated from patient tissues may predict patient-specific response to radiation therapy and have potential to be utilized for validation of biomarkers in drug discovery and treatment planning.

Medical subject headings