Brain tumors on slice: A novel platform for personalized therapeutic screening.

Sun, Yusha; Wang, Xin; Ming, Guo-Li; Song, Hongjun · Cell Rep Med · 2023

basic_science · Level V

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Abstract

Mann and Zhang et al. developed a robust ex vivo slice culture platform consisting of resected patient high- and low-grade glioma tissue engrafted onto rat organotypic brain slices, and interrogated tumor responses to clinically relevant therapeutics with a novel treatment-response algorithm.

Medical subject headings